| Universe | Description | Characters |
|---|---|---|
| Scott Pilgrim universe | narrative universe of the Scott Pilgrim comic book series and media franchise | 2 |
| Serenityverse | fictional universe of the Firefly franchise | 5 |
| Serial Experiments Lain universe | fictional universe from Serial Experiments Lain | 1 |
| Sherlock Holmes universe | fictional universe | 4 |
| Shogun universe | fictional universe | 1 |
| Shrek universe | fictional universe of the Shrek films | 6 |
| Silent Hill universe | fictional universe where the video game series Silent Hill takes place | 1 |
| Sonic the Hedgehog universe | fictional universe | 6 |
| Sonic X universe | narrative universe of the Japanese anime television series Sonic X | 1 |
| Sony's Spider-Man Universe | shared fictional universe | 1 |
| Soul Eater universe | narrative universe of the Soul Eater manga series | 1 |
| South Park universe | fictional universe of the animated television series South Park | 13 |
| Space Odyssey universe | fictional universe | 1 |
| SpongeBob SquarePants universe | narrative universe of the american animated television series SpongeBob SquarePants | 10 |
| Spy × Family universe | narrative universe of the Spy × Family manga series | 3 |
| StarCraft universe | 2 | |
| Stargate universe | fictional universe | 5 |
| Starship Troopers Universe | fictional universe based on R. A. Heinlein's Starship Troopers | 1 |
| Star Trek multiverse | fictional universe | 76 |
| Star Wars expanded to other media | fictional background of the Star Wars universe outside of the feature films | 25 |
| Star Wars universe | fictional background of Star Wars | 34 |
| Stranger Things universe | fictional universe where Netflix series Stranger Things is set | 13 |
| Super Mario universe | fictional universe | 5 |
| Supernatural universe | fictional universe of the television series Supernatural | 4 |
| Tarzan universe | fictional universe | 1 |
| Teenage Mutant Ninja Turtles universe | fictional universe | 1 |
| Terminator universe | fictional universe | 5 |
| That Time I Got Reincarnated as a Slime universe | narrative universe of the That Time I Got Reincarnated as a Slime light novel series | 1 |
| The 100 Girlfriends Who Really, Really, Really, Really, Really Love You universe | narrative universe of the The 100 Girlfriends Who Really, Really, Really, Really, Really Love You manga series | 1 |
| The Amazing Digital Circus universe | narrative universe of the Australian adult independent animated web series The Amazing Digital Circus | 7 |
| The Apothecary Diaries universe | narrative universe of the The Apothecary Diaries light novel series | 1 |
| The Coffin of Andy and Leyley universe | Narrative universe of the 2023 video game | 2 |
| The Elder Scrolls universe | fictional universe of The Elder Scrolls video game series | 3 |
| The Eminence in Shadow universe | narrative universe of the The Eminence in Shadow light novel series | 1 |
| The Emperor's New Groove universe | fictional universe where The Emperor's New Groove is set in | 1 |
| The Good Doctor universe | fictional universe | 1 |
| The Hitchhiker's Guide to the Galaxy universe | fictional universe | 5 |
| The Incredibles universe | fictional universe described in Disney/Pixar's The Incredibles franchise | 6 |
| The Last of Us universe | fictional universe of the The Last of Us video game series | 2 |
| The Lion King universe | fictional universe where The Lion King franchise is set in | 8 |
| The Little Mermaid universe | fictional universe | 2 |
| The Martian universe | fictional universe | 1 |
| The Powerpuff Girls universe | fictional universe of the animated television show The Powerpuff Girls | 3 |
| The Simpsons universe | fictional universe of the animated television series The Simpsons | 28 |
| The Vampire Diaries universe | narrative universe of the eponymous television show | 9 |
| The Walking Dead Comic Universe | narative universe of The Walking Dead comic book series and it's related spin-offs | 4 |
| The Walking Dead Television Universe | narative universe of The Walking Dead television series and it's related spin-offs | 16 |
| The Walking Dead universe | narrative universe of the eponymous media franchise | 35 |
| The Witcher universe | fictional universe | 14 |
| The World universe | fictional universe by Akira Toriyama | 41 |
| Tintin universe | set of literary elements of the Tintin works | 1 |
| Tokyo Ghoul universe | narrative universe of the manga series | 1 |
| Tolkien's legendarium | fictional universe by J. R. R. Tolkien | 34 |
| To Love Ru universe | narrative universe of the To Love Ru manga series | 1 |
| Tomb Raider universe | fictional universe where video game series Tomb Raider is set | 3 |
| Tom & Jerry universe | fictional universe of the Tom & Jerry media franchise | 2 |
| Top Cat universe | fictional universe of the Top Cat media franchise | 1 |
| Total Drama universe | fictional universe of the Total Drama franchise | 1 |
| Touhou Project universe | narrative universe of the bullet hell shoot 'em up video game series created by Team Shanghai Alice | 5 |
| Toy Story universe | fictional universe of the Toy Story films | 3 |
| Transformers universe | fictional universe | 10 |
| Treasure Island universe | fictional universe | 1 |
| True Blood fictional universe | fictional universe described in the book series The Southern Vampire Mysteries and in the TV series True Blood | 8 |
| Twilight universe | fictional universe | 4 |
| Twin Peaks | fictional world | 3 |
| Undertale universe | narrative universe of the 2015 video game Undertale | 4 |
| Universal Century | main setting of the Gundam anime metaseries | 1 |
| Universe of Kingdom Hearts | fictional universe | 3 |
| Universe of Mass Effect | the fictional universe of the Mass Effect franchise | 4 |
| universe of The Legend of Zelda | fictional universe | 4 |
| View Askewniverse | fictional universe and media franchise by Kevin Smith | 1 |
| Warcraft | video game series | 0 |
| Warcraft universe | 16 | |
| Warhammer 40,000 universe | fictional universe | 5 |
| Warhammer Fantasy | narrative universe of the Warhammer tabletop miniature wargame | 1 |
| Watchmen universe | narrative universe of the 1986 superhero comic book series by Alan Moore and Dave Gibbons | 6 |
| Whoniverse | setting of TV series Doctor Who and related creative works | 6 |
| Winnie the Pooh universe | fictional universe | 6 |
| Wolfenstein universe | fictional universe where video game series Wolfenstein is set | 1 |
| World of Avatar | fictional universe of the Avatar animated series and graphic novels | 28 |
| World of Ice and Fire | fictional world of A Song of Ice and Fire | 84 |
| Xenaverse | 1 | |
| Yakuza universe | fictional universe of Yakuza video game series | 4 |
| Yandere Simulator universe | fictional universe of the video game Yandere Simulator | 1 |
| Yu-Gi-Oh! universe | fictional universe of Yu-Gi-Oh! | 9 |
| Zootopia universe | narrative universe of the eponymous 2016 Walt Disney Animation Studios film | 2 |
| /universes/111732427 | fictional universe in Marvel Comics | 2 |
| /universes/109850855 | 4 |