| Work | Description | Characters |
|---|---|---|
| The End of the F***ing World | 2017 British comedy-drama television series | 3 |
| The Enemy | novel by Lee Child | 1 |
| The Enemy Within | 1966 episode of Star Trek: The Original Series (S1 E5) directed by Leo Penn | 6 |
| The Engineer's Thumb | 1923 film by George Ridgwell | 1 |
| The Enola Holmes Mysteries | young adult fiction series by Nancy Springer | 1 |
| The Entropy Effect | novel by Vonda McIntyre | 4 |
| The Equalizer | 2014 film directed by Antoine Fuqua | 1 |
| The Equalizer 2 | 2018 film directed by Antoine Fuqua | 1 |
| The Equalizer 3 | upcoming American action film | 1 |
| The Escape | Book by Dean Wesley Smith and Kristine Kathryn Rusch, from 1995 | 6 |
| The Expanse | American science fiction television series | 1 |
| The Expanse | series of space opera novels by James S. A. Corey | 1 |
| The Expanse | book | 3 |
| The Exploits of Moominpappa | the fourth book in the Moomin series by Tove Jansson | 1 |
| The Eye of the Beholder | novel | 6 |
| The Eyes of the Beholders | Book | 6 |
| The Fabulous Baron Munchausen | 1962 film by Karel Zeman | 1 |
| The Falcon and the Winter Soldier | American streaming television miniseries | 2 |
| The Familiar of Zero | Japanese anime television series | 1 |
| The Familiar of Zero | Japanese light novel series | 2 |
| The Family Corleone | novel by Edward Falco | 3 |
| The Fantastic Four | unreleased superhero film completed in 1994 directed by Oley Sassone | 1 |
| The Fantastic Four: First Steps | 2025 film directed by Matt Shakman | 1 |
| The Far Cry Experience | 2012 promotional web series | 1 |
| The Farther Shore | book by Christie Golden | 10 |
| The Fast and the Furious | 2001 film directed by Rob Cohen | 1 |
| The Fate of the Furious | 2017 film directed by F. Gary Gray | 1 |
| The Fate Of The Phoenix | Book by Sondra Marshak and Myrna Culbreath, from 1979 | 5 |
| The Fearful Summons | Book by Denny Martin Flinn | 5 |
| The Fellowship of the Ring | 1954 book by J. R. R. Tolkien | 6 |
| The Fifth Element | 1997 science fiction film by Luc Besson | 1 |
| The Final Fury | Book by Dafydd ab Hugh, from 1996 | 6 |
| The Final Nexus | book by Gene DeWeese | 5 |
| The Final Problem | short story by Sir Arthur Conan Doyle | 1 |
| The Final Reflection | book by John M. Ford | 4 |
| The Finding of Moses | poem | 1 |
| The Fire and the Rose | Book by David R. George III | 2 |
| The Flash | comic book series | 2 |
| The Flash | 2014 TV series | 7 |
| The Flash | 1990 American television series | 1 |
| The Flowers of Evil | 2009 Japanese manga series | 3 |
| The Forbidden Kingdom | 2008 film by Rob Minkoff | 1 |
| The Forsaken | episode of Star Trek: Deep Space Nine (S1 E17) | 3 |
| The Fortress of the Pearl | book by Michael Moorcock | 1 |
| The Fox and the Hound | 1981 American animated film | 1 |
| The Foxy Hunter | 1937 film by Dave Fleischer | 1 |
| The Fresh Prince of Bel-Air | television series | 1 |
| The Galactic Whirlpool | Book by David Gerrold, from 1980 | 5 |
| The Galileo Seven | episode of Star Trek: The Original Series (S1 E16) | 6 |
| The Garden | Book by Melissa Scott, from 1997 | 6 |
| The Garfield Show | French animated television series | 1 |
| The Girl from U.N.C.L.E. | television series | 1 |
| The Girl in the Spider's Web | novel by David Lagercrantz | 2 |
| The Girl Who Kicked the Hornets' Nest | 2007 Book by Stieg Larsson | 2 |
| The Girl Who Leapt Through Time | 2006 anime film directed by Mamoru Hosoda | 2 |
| The Girl Who Played with Fire | 2006 Book by Stieg Larsson | 2 |
| The Girl Who Takes an Eye for an Eye | fifth novel in the posthumously-published Millennium series of crime novels by Stieg Larsson | 2 |
| The Girl with the Dragon Tattoo | 2005 book by Stieg Larsson | 2 |
| The Godfather | 1972 American film directed by Francis Ford Coppola | 1 |
| The Godfather | 1969 novel by Mario Puzo | 7 |
| The Godfather | 2006 open world action-adventure video game | 3 |
| The Godfather II | 2009 video game | 3 |
| The Godfather Part II | 1974 film directed by Francis Ford Coppola | 1 |
| The Godfather Returns | novel by Mark Winegardner | 3 |
| The Godfather's Revenge | novel by Mark Winegardner | 2 |
| The Golden Compass | video game | 1 |
| The Golden Compass | 2007 fantasy film by Chris Weitz | 2 |
| The Golden Girls | American sitcom | 1 |
| The Good Doctor | American television series | 1 |
| The Good Place | 2016 American fantasy comedy television series | 10 |
| The Good That Men Do | Book by Michael A. Martin and Andy Mangels, from 2007 | 14 |
| The Great Ace Attorney: Adventures | 2015 video game | 1 |
| The Great Gatsby | novel by F. Scott Fitzgerald | 4 |
| The Great Starship Race | Book by Diane Carey | 5 |
| The Green Pastures | 1930 play by Marc Connelly | 1 |
| The Green Pastures | 1936 film by Marc Connelly, William Keighley | 1 |
| The Grim Adventures of Billy & Mandy | American animated television series | 3 |
| The Grinch | 2018 animated film by Yarrow Cheney and Scott Mosier | 1 |
| The Guardians of the Galaxy Holiday Special | Marvel Studios television special | 1 |
| The Gulag Archipelago | book by Aleksandr Solzhenitsyn | 1 |
| The Hakkenden | 1993 anime (original video animation) series | 1 |
| The Hammer of God | short story by G. K. Chesterton | 1 |
| The Hard Way | tenth Jack Reacher novel written by Lee Child | 1 |
| The Heroes of Olympus | children's fantasy adventure series, primarily 5 novels 2010 to 2014, in the Percy Jackson universe | 1 |
| The Hexer | 2001 film by Marek Brodzki | 7 |
| The Hexer | 2002 fantasy television series | 8 |
| The Hidden Words | Bahá'í scripture, written by Bahá'u'lláh around 1858 | 1 |
| The Hitchhiker's Guide to the Galaxy | 1979 book by Douglas Adams | 4 |
| The Hitchhiker's Guide to the Galaxy pentalogy | 1979-1992 series of five books by Douglas Adams | 2 |
| The Hobbit | 2003 video game | 1 |
| The Hobbit | fantasy novel by J. R. R. Tolkien | 9 |
| The Hobbit | 1982 interactive fiction computer game based on novel by J.R.R. Tolkien | 1 |
| The Hobbit: An Unexpected Journey | 2012 film directed by Peter Jackson | 4 |
| The Hobbit: The Battle of the Five Armies | 2014 epic fantasy adventure film directed by Peter Jackson | 4 |
| The Hobbit: The Desolation of Smaug | 2013 epic fantasy adventure film directed by Peter Jackson | 3 |
| The Hobbit trilogy | film series consisting of three films based on the 1937 novel "The Hobbit" by J. R. R. Tolkien | 3 |
| The Hollow | book | 1 |
| The Hollow Hills | 1973 Book by Mary Stewart | 1 |
| The Homecoming | episode of Star Trek: Deep Space Nine (S2 E1) | 9 |
| The Honourable Schoolboy | 1977 novel by John le Carré | 1 |