| Work | Description | Characters |
|---|---|---|
| Toy Story That Time Forgot | 2014 holiday television special | 1 |
| Trailer Park Boys | Canadian mockumentary television series | 1 |
| Training Day | 2001 film directed by Antoine Fuqua | 1 |
| Training Pigeons | 1936 film by Dave Fleischer | 1 |
| Trainspotting | 1993 novel by Irvine Welsh | 19 |
| Trainspotting | a 1996 comedy drama film | 10 |
| Train to the End of the World | Japanese anime television series | 1 |
| Train to the End of the World | Japanese manga series | 1 |
| Traitor Winds | Book by L.A. Graf | 4 |
| Transformers | Japanese–American media franchise, produced by Japanese toy company Takara Tomy and American toy company Hasbro | 9 |
| Transformers | 2007 science fiction film by Michael Bay | 1 |
| Transformers: Dark of the Moon | 2011 science fiction film directed by Michael Bay | 2 |
| Transformers: Revenge of the Fallen | 2009 science fiction film directed by Michael Bay | 2 |
| Transformers: The Headmasters | anime | 4 |
| Trash | episode of Firefly (S1 E11) | 2 |
| Treasure Island | 1934 film | 1 |
| Treasure Island | 1990 film directed by Fraser Clarke Heston | 1 |
| Treasure Island | novel by the Scottish author Robert Louis Stevenson | 1 |
| Treasure Island | 2007 television film directed by Hansjörg Thurn | 1 |
| Treasure Island | 1999 film by Peter Rowe | 1 |
| Treasure Island | 1985 film by Raúl Ruiz | 1 |
| Treasure Island | 2007 film by Alain Berbérian | 1 |
| Treasure Island | 1972 live-action film | 1 |
| Treasure Island | 1950 Disney adventure film directed by Byron Haskin | 1 |
| Treasure Island | 1966 television film directed by Wolfgang Liebeneiner | 1 |
| Treasure Island | 1920 film by Maurice Tourneur | 1 |
| Treasure Island | 2012 TV miniseries directed by Steve Barron | 1 |
| Treasure Planet | 2002 American animated science fiction film produced by Walt Disney Feature Animation | 1 |
| Treaty's Law | Book by Dean Wesley Smith and Kristine Kathryn Rusch, from 1997 | 5 |
| Trek to Madworld | Star Trek novel by Stephen Goldin | 5 |
| Trials and Tribble-Ations | Book by Diane Carey, from 1996 | 9 |
| Triangle: Imzadi II | 6 | |
| Trigun | Japanese anime television series | 1 |
| Trigun | Japanese manga series | 1 |
| Trigun: Badlands Rumble | 2010 anime film | 1 |
| Trill: Unjoined | Book by Andy Mangels and Michael A. Martin, from 2005 | 4 |
| Tripitaka | main religious text in Buddhism | 1 |
| Tripwire | book by Lee Child | 1 |
| Troy | 2004 film by Wolfgang Petersen | 1 |
| True Blood | American television drama series | 7 |
| True Detective | American television series | 4 |
| True Detective, season 1 | season of television series | 1 |
| True Tears | Japanese anime television series | 1 |
| Tsubasa: Reservoir Chronicle | 2005 Japanese anime by Clamp | 1 |
| Tsubasa: Reservoir Chronicle | 2005 Japanese manga by Clamp | 3 |
| Tsuredure Children | Japanese anime television series | 1 |
| Tsuredure Children | Japanese manga series | 1 |
| Tunnel Trough the Stars | Book by John Vornholt, from 1998 | 5 |
| Turtles Forever | 2009 American science fiction martial arts animated film | 1 |
| 'Twas the Night | 2001 movie directed by Nick Castle | 1 |
| Twenty Thousand Leagues Under the Sea | novel by Jules Verne | 1 |
| Twice Upon a Time | special episode of Doctor Who | 1 |
| Twilight | Star Trek novel by David R. George III, from 2002 | 18 |
| Twilight | series of vampire romance novels by Stephenie Meyer | 4 |
| Twilight's End | Book by Jerry Oltion, from 2000 | 5 |
| Twin Peaks | 1990's American drama television series | 3 |
| Twin Peaks | 2017 TV series | 2 |
| Twin Peaks: Fire Walk with Me | 1992 film by David Lynch | 2 |
| Two and a Half Men | TV series (2003-2015) | 5 |
| Uhura's Song | Science fiction novel | 4 |
| Ultimate Marvel vs. Capcom 3 | fighting video game | 9 |
| Ultimate Otaku Teacher | Japanese anime television series | 1 |
| Ultimate Otaku Teacher | Japanese manga series | 1 |
| Ultimate Spider-Man | 2005 video game | 1 |
| Ultimate Spider-Man | American superhero animated series | 3 |
| Ultra Street Fighter IV | 2014 video game | 1 |
| Ulysses | novel by the Irish author James Joyce | 4 |
| Umineko no Naku Koro ni | episodic video game | 1 |
| Umineko no Naku Koro ni Chiru | episodic video game | 1 |
| Umineko When They Cry | Japanese anime television series | 1 |
| Uncanny X-Men | comic book series | 14 |
| Uncharted 2: Among Thieves | 2009 video game | 1 |
| Uncharted 3: Drake's Deception | 2011 action-adventure third-person shooter platform video game | 1 |
| Uncharted 4: A Thief's End | 2016 video game | 1 |
| Uncharted: Drake's Fortune | 2007 video game published by Sony | 1 |
| Uncharted: Golden Abyss | video game | 1 |
| Uncharted: The Fourth Labyrinth | 1 | |
| Unconnected Marketeers | 2021 video game | 1 |
| Undead Nightmare | 2010 video game downloadable content | 1 |
| Undefined Fantastic Object | 2009 video game | 1 |
| Undertale | 2015 role-playing video game | 15 |
| Unfinished Tales | book | 2 |
| Unidentified Flying Oddball | 1979 film by Russ Mayberry | 3 |
| Unification | Book by Jeri Taylor, from 1991 | 6 |
| Unification III | episode of television series Star Trek: Discovery | 2 |
| Unity | Star Trek novel by S. D. Perry, from 2003 | 18 |
| Untitled third Fantastic Beasts film | 2022 film directed by David Yates | 2 |
| Unworthy | Book by Kirsten Beyer, from 2009 | 8 |
| Up | 2009 American 3D computer-animated comedy-adventure film | 2 |
| Up on the House Top | 1864 Christmas song by Benjamin Hanby | 1 |
| Ushio and Tora | manga | 1 |
| Vaas: Insanity | Far Cry DLC | 1 |
| Valhalla | Book by Nathan Archer, from 1995 | 5 |
| Valorant | 2020 free-to-play multiplayer first-person shooter video game developed by Riot Games | 12 |
| Vampire Hunter D | novel series by Hideyuki Kikuchi | 2 |
| Van Helsing | 2004 American period action horror film | 1 |
| Van Helsing: The London Assignment | 2004 animated short film | 1 |
| Vectors | Book by Dean Wesley Smith and Kristine Kathryn Rusch | 16 |
| Veep | 2012–2019 American comedy television series | 4 |
| Vendetta | Star Trek: The Next Generation tie-in novel | 7 |