| Work | Description | Characters |
|---|---|---|
| Prince of Persia: The Sands of Time | 2003 video game | 1 |
| Prince of Persia: The Sands of Time | 2010 American action fantasy film | 1 |
| Prince of Persia: The Two Thrones | 2005 video game | 1 |
| Prince of Persia: Warrior Within | 2004 video game | 1 |
| Prince of Stride | 2015 video game | 1 |
| Prince of Stride | Japanese multimedia series | 1 |
| Princess Connect! Re:Dive | 2018 video game | 1 |
| Princess Jellyfish | Japanese manga series | 1 |
| Princess Jellyfish | Japanese anime television series | 1 |
| Princess Mononoke | 1997 Japanese anime film | 3 |
| Princess Princess | Japanese manga series | 1 |
| Princess Principal | Japanese anime television series | 3 |
| Prison Break | American TV series | 1 |
| Prisoners of Peace | Book by John Peel, from 1994 | 2 |
| Prison School | Japanese manga series | 2 |
| Prison School | Japanese anime television series | 2 |
| Private Practice | American medical drama television program | 3 |
| Probe | Book by Margaret Wander Bonanno, from 1992 | 11 |
| Progress | episode of Star Trek: Deep Space Nine (S1 E15) | 8 |
| Project Hail Mary | 2026 film directed by Phil Lord and Christopher Miller | 3 |
| Project Hail Mary | 2021 novel by Andy Weir | 3 |
| Project M | unofficial video game | 1 |
| Project X Zone 2 | tactical role-playing video game | 1 |
| Prometheus Bound | ancient Greek tragedy by Aeschylus | 3 |
| Prototype | 2009 action-adventure open world video game | 1 |
| Prototype 2 | 2012 video game | 1 |
| Proud Helios | novel by Melissa Scott | 6 |
| Provenance of Shadows | Book by David R. George III | 4 |
| Proverbs | book of the Bible | 1 |
| Psalms | book of the Bible | 2 |
| Psych | American detective comedy-drama television series | 4 |
| Psycho-Pass | Japanese anime television series | 6 |
| Psycho tetralogy | Horror franchise | 1 |
| Pucca | TV series | 1 |
| Pudgy and the Lost Kitten | 1938 film by Dave Fleischer | 1 |
| Pudgy Picks a Fight! | 1937 film by Dave Fleischer | 1 |
| Pudgy Takes a Bow-Wow | 1937 film by Dave Fleischer | 1 |
| Pudgy the Watchman | 1938 film by Dave Fleischer | 1 |
| Puella Magi Madoka Magica | Japanese magical girl franchise | 6 |
| Puella Magi Madoka Magica: The Movie | film series directed by Akiyuki Shinbo | 6 |
| Pulp Fiction | 1994 American crime film directed by Quentin Tarantino | 3 |
| Punch Line | Japanese anime television series | 1 |
| Punisher: War Zone | 2008 comic book action film directed by Lexi Alexander | 1 |
| Pupipō! | Japanese anime television series | 1 |
| Pupipō! | Japanese manga series | 1 |
| Puss in Boots | 2011 animated adventure comedy film directed by Chris Miller | 2 |
| Puss in Boots: The Last Wish | 2022 animated film directed by Joel Crawford | 1 |
| Puss in Boots: The Three Diablos | 2012 film directed by Raman Hui | 1 |
| Pygmalion | play by George Bernard Shaw | 1 |
| Q&A | book | 21 |
| Q-in-Law | novel by Peter David | 8 |
| Q: Into the Storm | television series | 1 |
| Q-Space | Book by Greg Cox, from 1998 | 6 |
| Q-Squared | novel by Peter David | 7 |
| Q-Strike | Book by Greg Cox | 6 |
| Quantum Leap | television series (1989-1993) | 1 |
| Quantum of Solace | 2008 film by Marc Forster | 1 |
| Quark's Lucky Seven | Mission in Star Trek: Online | 1 |
| Quartett | opera by Luca Francesconi | 1 |
| Queen's Shadow | novel by E. K. Johnston | 2 |
| Queer Visitors from the Marvelous Land of Oz | newspaper comic strip by L. Frank Baum | 1 |
| Quo Vadis | Historical novel written by Henryk Sienkiewicz | 1 |
| Quo Vadis? | 1985 miniseries by Franco Rossi | 1 |
| Quran | central religious text of Islam | 8 |
| Q-Zone | Book by Greg Cox, from 1998 | 6 |
| Ragnarok | Book by Nathan Archer, from 1995 | 6 |
| Raiders of the Lost Ark | 1981 film by Steven Spielberg | 1 |
| Rainbow Days | Japanese manga series | 1 |
| Rainbow Days | Japanese anime television series | 1 |
| Raise the Dawn | Star Trek novel by David R. George III | 1 |
| Ralph Breaks the Internet | 2018 animated film produced by Walt Disney Animation Studios | 8 |
| Rambo | film series | 1 |
| Rango | 2011 video game | 1 |
| Rango | 2011 American animated film | 1 |
| Ranma ½ | Japanese media franchise | 5 |
| Rapunzel's Tangled Adventure | American animated television series | 2 |
| Ratatouille | 2007 animated film directed by Brad Bird | 1 |
| Raya and the Last Dragon | 2021 animated film directed by Don Hall and Carlos López Estrada | 1 |
| Reacher | TV series based on the Lee Child character | 1 |
| Recovery | Book by Jeanne Kalogridis, from 1995 | 5 |
| Rectify | 2013–2016 American television series | 5 |
| Red Dead Redemption | 2010 action-adventure video game | 2 |
| Red Dead Redemption 2 | 2018 western-themed action-adventure video game | 3 |
| Red Dead Redemption: The Man from Blackwater | 2010 film | 1 |
| Red Dragon | 2002 American thriller film directed by Brett Ratner | 2 |
| Red Dragon | 1981 book by Thomas Harris | 2 |
| Red Hot Mamma | 1934 film by Dave Fleischer | 1 |
| Red Nails | Conan novella by Robert E. Howard | 1 |
| Red Sector | Book by Diane Carey, from 1999 | 9 |
| Regular Show | American animated television series created by J. G. Quintel for Cartoon Network | 5 |
| Relics | Book by Michael Jan Friedman, from 1992 | 7 |
| Remembrance | 1st Episode of Star Trek: Picard | 4 |
| Remembrances | episode of The Legend of Korra (S4 E8) | 1 |
| Renegade | Book by Gene DeWeese | 5 |
| Requiem | 1994 novel by Michael Jan Friedman & Kevin Ryan | 6 |
| Requiem for a Dream | 2000 film by Darren Aronofsky | 1 |
| Requiem for a Dream | 1978 novel | 1 |
| Resident Evil | video game and media franchise | 3 |
| Resident Evil | 1996 survival horror video game | 1 |
| Resident Evil 2 | 2019 survival horror video game remake developed by Capcom | 1 |