| Work | Description | Characters |
|---|---|---|
| Rick and Morty | American comic book series based on Rick and Morty | 1 |
| Rick and Morty: The Anime | 2024 Japanese-American anime television series | 1 |
| Rick and Morty: The Non-Canonical Adventures | Rick and Morty claymation web series | 1 |
| Riddle Story of Devil | Japanese anime television series | 1 |
| Riddle Story of Devil | Japanese manga series | 1 |
| Ride Your Wave | 2019 Japanese animated film | 1 |
| Riding the Rails | 1938 film by Dave Fleischer | 1 |
| Rilla of Ingleside | book by Lucy Maud Montgomery | 1 |
| Ripley | 2024 television series | 1 |
| Rise of the Planet of the Apes | 2011 film directed by Rupert Wyatt | 2 |
| Rise of the Teenage Mutant Ninja Turtles | American animated 2018 television series | 1 |
| Rise of the Tomb Raider | video game | 1 |
| Rising Son | Book by S. D. Perry, from 2003 | 12 |
| Rita Hayworth and Shawshank Redemption | book | 1 |
| Riverdale | American teen drama television series | 2 |
| Road Dogs | 2009 novel by Elmore Leonard | 1 |
| Road without return | rock opera by the Russian band ESSE | 1 |
| Robert Ludlum's The Bourne Conspiracy | 2008 third-person action stealth video game | 1 |
| Robin Hood | The Legend of Robin Hood | 1 |
| Robin Hood | 1973 American animated film | 1 |
| Rocko's Modern Life | television series | 1 |
| Rocky | boxing saga of films all written by and starring Sylvester Stallone as Rocky Balboa. | 1 |
| Rogue | book by Michael A. Martin | 6 |
| Rogue One | 2016 American epic space opera film in the Star Wars franchise directed by Gareth Edwards | 7 |
| Rogue Saucer | novel by John Vornholt | 6 |
| Rome | TV series | 3 |
| Romeo and Juliet | tragedy by William Shakespeare | 2 |
| Romulan Imperial Minefield | Mission in Star Trek: Online | 1 |
| Ronja, the Robber's Daughter | Japanese anime television series | 1 |
| Room Camp | Japanese anime television series | 1 |
| Rosetta | Book by Dave Stern from Pocket Books, from 2006 | 3 |
| Rough Beasts of Empire | Star Trek novel by David R. George III | 4 |
| Roughnecks: Starship Troopers Chronicles | television series | 1 |
| Round about our Coal Fire | ca. 1730 English pamphlet | 1 |
| Rugrats | American children's television series | 2 |
| Rugrats Pre-School Daze | television series | 1 |
| Rules Of Engagement | book by Peter Morwood | 5 |
| Runaway Brain | 1995 Mickey Mouse short directed by Chris Bailey | 1 |
| Runaway Horses | novel by Yukio Mishima | 1 |
| Running Blind | book | 1 |
| Rurouni Kenshin | Japanese media franchise | 1 |
| Ruth | book of the Bible | 1 |
| Ryanverse | series of novels by Tom Clancy | 1 |
| Sabrina, Down Under | 1998 television film | 1 |
| Sabrina: Friends Forever | 2002 television film | 2 |
| Sabrina Goes to Rome | 1998 television film directed by Tibor Takács | 1 |
| Sabrina: Secrets of a Teenage Witch | Animated TV Series | 2 |
| Sabrina's Secret Life | television series | 2 |
| Sabrina: The Animated Series | American animated television series | 2 |
| Sabrina the Teenage Witch | 1996 television film directed by Tibor Takács | 2 |
| Sabrina the Teenage Witch | television series | 2 |
| Sabrina the Teenage Witch | comic book series published by Archie Comics about the adventures of a fictional American teenager named Sabrina Spellman | 2 |
| Sabrina, the Teenage Witch | American sitcom | 2 |
| Sacraments of Fire | Star Trek novel by David R. George III | 1 |
| Sacrifice of Angels | Book by Diane Carey, from 1998 | 11 |
| Sacrifice of Angels | episode of Star Trek: Deep Space Nine (S6 E6) | 1 |
| Sad Cypress | book | 1 |
| Saekano | Japanese light novel, manga, and anime series | 5 |
| Saekano: How to Raise a Boring Girlfriend | Japanese manga series | 5 |
| Safe | episode of Firefly (S1 E5) | 2 |
| Sailor Moon | Japanese manga series | 5 |
| Sailor Moon | 1992 television anime directed by Junichi Sato, Takuya Igarashi and Kunihiko Ikuhara | 5 |
| Sailor Moon | Japanese manga series | 10 |
| Sailor Moon Crystal | original net animation series produced by Toei Animation and directed by Munehisa Sakai, produced in commemoration of the twentieth anniversary of the shōjo manga series Sailor Moon | 4 |
| Saint Beast: Seijū Kōrin-hen | Japanese anime television series | 1 |
| Saints Row | 2006 open world action-adventure video game | 1 |
| Saints Row 2 | 2008 open world action-adventure video game developed by Volition, Inc | 1 |
| Saints Row: Gat out of Hell | video game | 1 |
| Saints Row IV | 2013 open world action-adventure video game | 1 |
| Saints Row: The Third | 2011 video game | 1 |
| Sally Swing | 1938 film by Dave Fleischer | 1 |
| Saludos Amigos | 1942 US animated film | 1 |
| Samurai Champloo | Japanese anime television series | 1 |
| Samurai Flamenco | Japanese anime television series | 1 |
| Samurai Jack | American animated television series | 2 |
| Samurai Jack: The Amulet of Time | 2003 video game | 1 |
| Samurai Jack: The Shadow of Aku | 2004 video game | 2 |
| Sanctuary | science fiction-fantasy TV series from Canada | 2 |
| Sanctuary | Book by John Vornholt, from 1992 | 5 |
| Sandworms of Dune | novel by Kevin J. Anderson | 2 |
| San Paolo | 2000 television film directed by Roger Young | 1 |
| Santa Claus Conquers the Martians | 1964 film by Nicholas Webster | 1 |
| Saratoga | Star Trek novel by Michael Jan Friedman | 6 |
| Sarek | novel by Ann C. Crispin | 2 |
| Saved by the Bell | American television sitcom (1989-1993) | 1 |
| Saved by the Bell: Hawaiian Style | 1992 television film directed by Don Barnhart | 1 |
| Saved by the Bell: The College Years | American television series | 1 |
| Saved by the Bell: The New Class | American sitcom television series | 1 |
| Saved by the Bell: Wedding in Las Vegas | 1994 television film directed by Jeff Melman | 1 |
| Saw | film series | 1 |
| Say Anything... | 1989 American teen romantic comedy-drama film | 2 |
| Sayonara, Zetsubou-Sensei | Japanese manga series | 1 |
| Scandal | 2012 American political thriller television series | 1 |
| Scandal, season 7 | season of television series | 1 |
| Scared Shrekless | 2010 film directed by Gary Trousdale | 3 |
| Scarface | 1983 crime drama film directed by Brian De Palma | 1 |
| Scarface: The World Is Yours | 2006 video game | 1 |
| Scarlett | 1991 novel by Alexandra Ripley | 1 |
| Scarlet Weather Rhapsody | 2008 video game | 3 |
| Schitt's Creek | Canadian television sitcom | 7 |