| Work | Description | Characters |
|---|---|---|
| Resident Evil 2 | 1998 survival horror video game | 1 |
| Resident Evil 3 | 2020 survival horror video game remake developed by Capcom | 1 |
| Resident Evil 3: Nemesis | 1999 survival horror video game | 2 |
| Resident Evil 4 | 2005 survival horror video game | 1 |
| Resident Evil 5 | video game | 2 |
| Resident Evil 6 | 2012 survival horror video game | 1 |
| Resident Evil: Damnation | 2012 film by Makoto Kamiya | 1 |
| Resident Evil: Death Island | 2023 film by Eiichirō Hasumi | 1 |
| Resident Evil: Degeneration | 2008 animated film directed by Makoto Kamiya | 1 |
| Resident Evil: Infinite Darkness | 2021 CGI animation anime series | 1 |
| Resident Evil: Retribution | 2012 film directed by Paul W. S. Anderson | 1 |
| Resident Evil: Revelations | 2012 survival horror video game | 1 |
| Resident Evil: Revelations 2 | 2015 survival horror video game | 1 |
| Resident Evil Re:Verse | upcoming 2022 survival horror multiplayer video game developed by Capcom | 1 |
| Resident Evil: Vendetta | 2017 film by Takanori Tsujimoto | 1 |
| Resident Evil: Welcome to Raccoon City | 2021 film directed by Johannes Roberts | 1 |
| Resistance | Star Trek: The Next Generation novel | 13 |
| Return of the Jedi | 1983 American epic space opera film directed by Richard Marquand | 12 |
| Return of the Man from U.N.C.L.E. | 1983 television film directed by Ray Austin | 1 |
| Return to Babel | Mission in Star Trek: Online | 1 |
| Return to Labyrinth | manga | 1 |
| Reunion | Book by Michael Jan Friedman, from 1991 | 6 |
| Revelation and Dust | Star Trek novel by David R. George III | 1 |
| Revelation of John | Final book of the New Testament | 1 |
| Revolutionary Girl Utena | Japanese anime television series | 2 |
| Re:Zero − Starting Life in Another World | Japanese anime television series | 8 |
| Re:Zero − Starting Life in Another World | Japanese light novel series | 6 |
| Rhesus | Athenian tragedy attributed to Euripides | 1 |
| Rhythm on the Reservation | 1939 film by Dave Fleischer | 1 |
| Rick and Morty | American comic book series based on Rick and Morty | 1 |
| Rick and Morty | American animated television series | 5 |
| Rick and Morty: The Anime | 2024 Japanese-American anime television series | 1 |
| Rick and Morty: The Non-Canonical Adventures | Rick and Morty claymation web series | 1 |
| Riddle Story of Devil | Japanese anime television series | 1 |
| Riddle Story of Devil | Japanese manga series | 1 |
| Ride Your Wave | 2019 Japanese animated film | 1 |
| Riding the Rails | 1938 film by Dave Fleischer | 1 |
| Rilla of Ingleside | book by Lucy Maud Montgomery | 1 |
| Ripley | 2024 television series | 1 |
| Rise of the Planet of the Apes | 2011 film directed by Rupert Wyatt | 2 |
| Rise of the Teenage Mutant Ninja Turtles | American animated 2018 television series | 1 |
| Rise of the Tomb Raider | video game | 1 |
| Rising Son | Book by S. D. Perry, from 2003 | 12 |
| Rita Hayworth and Shawshank Redemption | book | 1 |
| Riverdale | American teen drama television series | 2 |
| Road Dogs | 2009 novel by Elmore Leonard | 1 |
| Road without return | rock opera by the Russian band ESSE | 1 |
| Robert Ludlum's The Bourne Conspiracy | 2008 third-person action stealth video game | 1 |
| Robin Hood | 1973 American animated film | 1 |
| Robin Hood | The Legend of Robin Hood | 1 |
| Rocko's Modern Life | television series | 1 |
| Rocky | boxing saga of films all written by and starring Sylvester Stallone as Rocky Balboa. | 1 |
| Rogue | book by Michael A. Martin | 6 |
| Rogue One | 2016 American epic space opera film in the Star Wars franchise directed by Gareth Edwards | 7 |
| Rogue Saucer | novel by John Vornholt | 6 |
| Rokka: Braves of the Six Flowers | Japanese anime television series | 1 |
| Rokka: Braves of the Six Flowers | Japanese light novel series | 1 |
| Rome | TV series | 3 |
| Romeo and Juliet | tragedy by William Shakespeare | 2 |
| Romulan Imperial Minefield | Mission in Star Trek: Online | 1 |
| Ronja, the Robber's Daughter | Japanese anime television series | 1 |
| Room Camp | Japanese anime television series | 1 |
| Rosario + Vampire | Japanese anime television series | 1 |
| Rosario + Vampire | Japanese manga series | 1 |
| Rosetta | Book by Dave Stern from Pocket Books, from 2006 | 3 |
| Rough Beasts of Empire | Star Trek novel by David R. George III | 4 |
| Roughnecks: Starship Troopers Chronicles | television series | 1 |
| Round about our Coal Fire | ca. 1730 English pamphlet | 1 |
| Rugrats | American children's television series | 2 |
| Rugrats Pre-School Daze | television series | 1 |
| Rules Of Engagement | book by Peter Morwood | 5 |
| Runaway Brain | 1995 Mickey Mouse short directed by Chris Bailey | 1 |
| Runaway Horses | novel by Yukio Mishima | 1 |
| Running Blind | book | 1 |
| Rurouni Kenshin | Japanese media franchise | 1 |
| Ruth | book of the Bible | 1 |
| Ryanverse | series of novels by Tom Clancy | 1 |
| Sabrina, Down Under | 1998 television film | 1 |
| Sabrina: Friends Forever | 2002 television film | 2 |
| Sabrina Goes to Rome | 1998 television film directed by Tibor Takács | 1 |
| Sabrina: Secrets of a Teenage Witch | Animated TV Series | 2 |
| Sabrina's Secret Life | television series | 2 |
| Sabrina: The Animated Series | American animated television series | 2 |
| Sabrina the Teenage Witch | comic book series published by Archie Comics about the adventures of a fictional American teenager named Sabrina Spellman | 2 |
| Sabrina the Teenage Witch | television series | 2 |
| Sabrina the Teenage Witch | 1996 television film directed by Tibor Takács | 2 |
| Sabrina, the Teenage Witch | American sitcom | 2 |
| Sacraments of Fire | Star Trek novel by David R. George III | 1 |
| Sacrifice of Angels | episode of Star Trek: Deep Space Nine (S6 E6) | 1 |
| Sacrifice of Angels | Book by Diane Carey, from 1998 | 11 |
| Sad Cypress | book | 1 |
| Saekano | Japanese light novel, manga, and anime series | 5 |
| Saekano: How to Raise a Boring Girlfriend | Japanese manga series | 5 |
| Safe | episode of Firefly (S1 E5) | 2 |
| Sailor Moon | 1992 television anime directed by Junichi Sato, Takuya Igarashi and Kunihiko Ikuhara | 5 |
| Sailor Moon | Japanese manga series | 5 |
| Sailor Moon | Japanese manga series | 10 |
| Sailor Moon Crystal | original net animation series produced by Toei Animation and directed by Munehisa Sakai, produced in commemoration of the twentieth anniversary of the shōjo manga series Sailor Moon | 4 |
| Saint Beast: Seijū Kōrin-hen | Japanese anime television series | 1 |
| Saints Row | 2006 open world action-adventure video game | 1 |