| Work | Description | Characters |
|---|---|---|
| DC Comics Presents | comic book series | 3 |
| DC Nation Shorts | 8 | |
| DC Showcase: Adam Strange | 2020 film directed by Butch Lukic | 1 |
| DC Showcase: Catwoman | 2011 film directed by Lauren Montgomery | 1 |
| DC Super Hero Girls | American animated action-adventure television series | 1 |
| DC Super Hero Girls | 2015 American television series by Warner Bros. Animation | 6 |
| DC Super Hero Girls: Hero of the Year | 2016 film | 1 |
| DC Super Hero Girls: Intergalactic Games | 2017 film | 2 |
| DC Universe Online | 2011 video game | 5 |
| Dead by Daylight | 2016 asymmetric survival horror video game developed by Behaviour Interactive | 4 |
| Dead Man's Folly | book | 1 |
| Dead Men's Trousers | Irvine Welsh's novel | 3 |
| Dead Poets Society | 1989 film directed by Peter Weir | 1 |
| Deadpool | 2016 superhero film produced by Marvel Entertainment | 1 |
| Deadpool 2 | 2018 film directed by David Leitch | 6 |
| Dealing with the Pied Piper of Hameln | German legend | 1 |
| Dear Evan Hansen | 2016 musical | 1 |
| Death Becomes Her | 1992 film by Robert Zemeckis | 2 |
| Death Count | Book by L.A. Graf, from 1992 | 5 |
| Death in the Clouds | book | 1 |
| Death in Winter | novel by Michael Jan Friedman | 10 |
| Death Mask | story by Seishi Yokomizo | 1 |
| Death Note | manga series | 10 |
| Death Note | Japanese anime television series | 4 |
| Death Note: The Musical | musical based on the franchise | 1 |
| Death of a Neutron Star | Book by Yoji Kondo, from 1999 | 6 |
| Death on the Nile | 1937 Agatha Christie novel | 1 |
| Death Parade | Japanese anime television series | 3 |
| Death's Angel | Book by Kathleen Sky, from 1981 | 5 |
| Death Stranding | 2019 open world action video game developed by Kojima Productions | 2 |
| Debtors' Planet | Book by W.R. Thompson, from 1994 | 7 |
| Deceived | book by Paul S. Kemp | 1 |
| Deep Domain | book by Howard Weinstein | 5 |
| Deep Duck Trouble Starring Donald Duck | 1993 platform video game | 1 |
| Delicious in Dungeon | Japanese anime television series | 6 |
| Delicious in Dungeon | Japanese manga series | 6 |
| Deltarune | 2018 independent video game developed by Toby Fox | 13 |
| De Mantel der Liefde | 1978 film by Adriaan Ditvoorst | 1 |
| Demon King Daimao | Japanese light novel series | 1 |
| Demons | Star Trek: The Original Series novel written by J.M. Dillard | 4 |
| Demon Slayer: Kimetsu no Yaiba | Japanese manga series | 4 |
| Demon Slayer: Kimetsu no Yaiba | Japanese anime television series | 4 |
| Demons of Air and Darkness | Star Trek novel by Keith R. A. DeCandido, from 2001 | 15 |
| Denial of Destiny | science fiction role-playing game adventure | 2 |
| Descendants | 2015 film directed by Kenny Ortega | 3 |
| Descent | Book by Diane Carey | 5 |
| Descent | episode of Star Trek: The Next Generation (S6 E26) | 1 |
| Desert Crossing | episode of Star Trek: Enterprise (S1 E24) | 4 |
| Desperate Housewives | American comedy-drama TV series | 4 |
| Despicable Me | 2010 American computer-animated 3D comedy film | 1 |
| Destination: Treasure Island | 2006 video game | 1 |
| Detective Comics | title used for two American comic book series | 5 |
| Detective Conan | Japanese media franchise | 1 |
| Detective Pikachu | 2019 film by Rob Letterman | 1 |
| Detroit: Become Human | 2018 adventure video game developed by Quantic Dream | 12 |
| Deuteronomy | fifth book of the Old testament | 3 |
| De vier dochters Bennet | 1961 television miniseries | 7 |
| Devil in the Sky | Book by Greg Cox and John Gregory Betancourt, from 1995 | 5 |
| Devilman | 1972 Japanese manga by Go Nagai | 2 |
| Devil May Cry | 2001 video game | 2 |
| Devil May Cry | video game series | 2 |
| Devil May Cry 2 | video game | 1 |
| Devil May Cry 3 | 1 | |
| Devil May Cry 3: Dante's Awakening | video game | 2 |
| Devil May Cry 4 | video game | 4 |
| Devil May Cry 5 | 2019 action-adventure hack and slash video game developed by Capcom | 3 |
| Devil World | Book by Gordon Eklund, from 1979 | 5 |
| Dexter | American crime drama television series (2006–2013) | 10 |
| D-Frag! | Japanese manga series | 1 |
| D-Frag! | Japanese anime television series | 1 |
| D.Gray-man | Japanese anime television series | 1 |
| D.Gray-man | Japanese manga series | 2 |
| Diablo IV | 2023 role-playing video game developed by Blizzard Entertainment | 1 |
| Diamond Is Unbreakable | the fourth story arc of the Japanese manga series JoJo's Bizarre Adventure, written and illustrated by Hirohiko Araki | 4 |
| Diamonds Are Forever | 1971 James Bond film by Guy Hamilton | 1 |
| Diary of a Wimpy Kid | 2010 film directed by Thor Freudenthal | 2 |
| Diary of a Wimpy Kid | film series | 1 |
| Diary of a Wimpy Kid | series of books | 4 |
| Diary of a Wimpy Kid: Dog Days (film) | 2012 film by David Bowers | 2 |
| Diary of a Wimpy Kid: Rodrick Rules (film) | 2011 film by David Bowers | 2 |
| Diary of a Wimpy Kid: The Long Haul | 2017 American film by David Bowers | 2 |
| Die Another Day | 2002 spy film in the James Bond series directed by Lee Tamahori | 1 |
| Die Hard | 1988 film directed by John McTiernan | 1 |
| Die Israeliten in der Wüste | oratorio by Carl Philipp Emanuel Bach | 1 |
| Die Trying | episode of television series Star Trek: Discovery | 1 |
| Die Trying | novel by Lee Child | 1 |
| Ding Dong Doggie | 1937 film by Dave Fleischer | 1 |
| Dirk Gently | British comedy detective drama TV series | 1 |
| Dirk Gently's Holistic Detective Agency | television series | 1 |
| Dirk Gently's Holistic Detective Agency | 1987 book by Douglas Adams | 1 |
| Disco Elysium | 2019 role-playing video game | 1 |
| Dishonored | 2012 action-adventure video game | 1 |
| Disney Dreamlight Valley | life simulation and adventure video game | 3 |
| Disney Friends | 2007 video game featuring Disney and Pixar characters from Lilo & Stitch, Finding Nemo, Winnie the Pooh, and The Lion King | 1 |
| Disney Infinity 2.0: Marvel Super Heroes | 2014 toys-to-life sandbox video game | 1 |
| Disney Infinity 3.0 | 2015 action-adventure toys-to-life video game | 1 |
| Disney's Extreme Skate Adventure | 2003 video game | 1 |
| Disney's Lilo & Stitch | 2002 Game Boy Advance video game tie-in to Lilo & Stitch | 2 |
| Disney's Stitch: Experiment 626 | 2002 prequel video game tie-in to Lilo & Stitch | 1 |
| Dissidia 012 Final Fantasy | video game | 2 |